Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or even no symptoms. Researchers in previous studies have discovered one reason why: cells ...

Strokes lead to irreversible damage to the brain and are one of the most common causes of dependency or death. As the cellular reactions to a cerebral infarction are not yet fully understood, there is ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these ...

Septins are a conserved family of GTP-binding proteins that assemble into filamentous structures, earning them recognition as the fourth component of the cytoskeleton alongside actin, microtubules and ...

A new study from Whitehead Institute Member Jonathan Weissman reveals how cells may activate a compensation system that can, in some cases, reduce the effects of potentially harmful genetic mutations.

Caspases are a family of proteolytic enzymes that play a central role in apoptosis, the regulated process of programmed cell death essential for development, homeostasis and the clearance of damaged ...

As we age, our cells don’t just wear down—they reorganize. Researchers found that cells actively remodel a key structure called the endoplasmic reticulum, reducing protein-producing regions while ...

Every year, the media informs us that we’re on the cusp of the golden age of something. While the expected trend often comes to fruition, it’s rarely as smooth a process as advertised. Drug discovery ...

Many biological processes are regulated by electricity-from nerve impulses to heartbeats to the movement of molecules in and out of cells. A new study by Scripps Research scientists reveals a ...

Microtubules perform an active role in communication within the cell by transmitting received signals to the cell's functional units. Researchers at the Paul Scherrer Institute PSI and the Department ...